ARHGEF6 (Human) Matched Antibody Pair
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More Files
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Sandwich ELISA detection sensitivity ranging from approximately 729x to 3x dilution of the ARHGEF6 293T overexpression lysate (non-denatured).
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human ARHGEF6.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Quality Control Testing
Standard curve using ARHGEF6 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 729x to 3x dilution of the ARHGEF6 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-ARHGEF6 (100 ug)
2. Detection antibody: rabbit purified polyclonal anti-ARHGEF6 (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — ARHGEF6
Entrez GeneID
9459Gene Name
ARHGEF6
Gene Alias
COOL2, Cool-2, KIAA0006, MRX46, PIXA, alpha-PIX, alphaPIX
Gene Description
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq
Other Designations
OTTHUMP00000062283|PAK-interacting exchange factor, alpha|Rac/Cdc42 guanine exchange factor (GEF) 6|Rac/Cdc42 guanine nucleotide exchange factor 6|mental retardation, X-linked 46|rho guanine nucleotide exchange factor 6
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Interactome
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Pathway
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Disease
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