HOMER3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human HOMER3 protein.
Immunogen
HOMER3 (NP_004829.2, 1 a.a. ~ 361 a.a) full-length human protein.
Sequence
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKSQDGGELTSPALGLASHQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVRLFELSELREGLARLAEAAP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (90)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
HOMER3 MaxPab polyclonal antibody. Western Blot analysis of HOMER3 expression in human spleen.Western Blot (Cell lysate)
HOMER3 MaxPab polyclonal antibody. Western Blot analysis of HOMER3 expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of HOMER3 expression in transfected 293T cell line (H00009454-T01) by HOMER3 MaxPab polyclonal antibody.
Lane 1: HOMER3 transfected lysate(39.71 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — HOMER3
Entrez GeneID
9454GeneBank Accession#
NM_004838.2Protein Accession#
NP_004829.2Gene Name
HOMER3
Gene Alias
HOMER-3
Gene Description
homer homolog 3 (Drosophila)
Omim ID
604800Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants
Other Designations
Homer, neuronal immediate early gene, 3|Homer-3D protein
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Interactome
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Disease
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