AIM2 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human AIM2 protein.
Immunogen
AIM2 (NP_004824.1, 1 a.a. ~ 343 a.a) full-length human protein.
Sequence
MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVSAVMKTIRIFQKLNYMLLAKRLQEEKEKVDKQYKSVTKPKPLSQAEMSPAASAAIRNDVAKQRAAPKVSPHVKPEQKQMVAQQESIREGFQKRCLPVMVLKAKKPFTFETQEGKQEMFHATVATEKEFFFVKVFNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRKAGETPKINTLQTQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCKEGDKVRLTFFTLSKNGEKLQLTSGVHSTIKVIKAKKKT
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (55)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of AIM2 expression in transfected 293T cell line (H00009447-T03) by AIM2 MaxPab polyclonal antibody.
Lane 1: AIM2 transfected lysate(39.00 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of AIM2 transfected lysate using anti-AIM2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with AIM2 purified MaxPab mouse polyclonal antibody (B01P) (H00009447-B01P). -
Gene Info — AIM2
Entrez GeneID
9447GeneBank Accession#
NM_004833Protein Accession#
NP_004824.1Gene Name
AIM2
Gene Alias
PYHIN4
Gene Description
absent in melanoma 2
Omim ID
604578Gene Ontology
HyperlinkGene Summary
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq
Other Designations
OTTHUMP00000035296
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Interactome
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Disease
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Publication Reference
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Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.
Adamczak SE, de Rivero Vaccari JP, Dale G, Brand Iii FJ, Nonner D, Bullock M, Dahl GP, Dietrich W, Keane RW.
Journal of Cerebral Blood Flow and Metabolism 2014 Apr; 34(4):621.
Application:IP-WB, WB-Ti, Rat, Embryonic cortical neurons.
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Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.
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