QKI 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-QKI full-length
Host
Human
Theoretical MW (kDa)
35.1
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-QKI antibody (H00009444-B01) by Western Blots.
SDS-PAGE Gel
QKI transfected lysate.
Western Blot
Lane 1: QKI transfected lysate ( 35.1 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — QKI
Entrez GeneID
9444GeneBank Accession#
NM_206853Protein Accession#
NP_996735Gene Name
QKI
Gene Alias
DKFZp586I0923, Hqk, QK, QK1, QK3
Gene Description
quaking homolog, KH domain RNA binding (mouse)
Omim ID
609590Gene Ontology
HyperlinkGene Summary
QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).[supplied by OMIM
Other Designations
OTTHUMP00000017581|OTTHUMP00000017582|OTTHUMP00000017583|RNA binding protein HQK|homolog of mouse quaking QKI (KH domain RNA binding protein)|quaking homolog, KH domain RNA binding
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Interactome
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Disease
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