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MED17 rabbit monoclonal antibody

  • Catalog # : H00009440-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human MED17 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human MED17 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human MED17 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9440
  • GeneBank Accession#:
  • MED17
  • Gene Name:
  • MED17
  • Gene Alias:
  • CRSP6,CRSP77,DRIP80,FLJ10812,TRAP80
  • Gene Description:
  • mediator complex subunit 17
  • Gene Summary:
  • The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq
  • Other Designations:
  • cofactor required for Sp1 transcriptional activation, subunit 6 (77kD),cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa,thyroid hormone receptor-associated protein, 80-KD subunit,vitamin D receptor interacting protein 80-kD
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