CDY2A monoclonal antibody (M12), clone 4C8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDY2A.
Immunogen
CDY2A (NP_004816, 123 a.a. ~ 214 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ASTLSDTKNMEIINSTIETLAPDSPFDHKKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSHPGAEQTGIQNKTQMHPLMSQMSGS
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.86 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CDY2A is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — CDY2A
Entrez GeneID
9426GeneBank Accession#
NM_004825Protein Accession#
NP_004816Gene Name
CDY2A
Gene Alias
CDY, CDY2
Gene Description
chromodomain protein, Y-linked, 2A
Omim ID
400018Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. [provided by RefSeq
Other Designations
Y chromosome chromodomain protein 2A|chromodomain protein, Y chromosome, 2|testis-specific chromodomain protein Y protein 2
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