TJP2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TJP2 partial ORF ( NP_004808, 121 a.a. - 218 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TJP2
Entrez GeneID
9414GeneBank Accession#
NM_004817Protein Accession#
NP_004808Gene Name
TJP2
Gene Alias
MGC26306, X104, ZO-2, ZO2
Gene Description
tight junction protein 2 (zona occludens 2)
Gene Ontology
HyperlinkGene Summary
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM
Other Designations
Friedreich ataxia region gene X104 (tight junction protein ZO-2)|OTTHUMP00000021431|OTTHUMP00000063359
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Interactome
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Pathway
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