TJP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TJP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TJP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TJP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TJP2
Entrez GeneID
9414GeneBank Accession#
TJP2Gene Name
TJP2
Gene Alias
MGC26306, X104, ZO-2, ZO2
Gene Description
tight junction protein 2 (zona occludens 2)
Gene Ontology
HyperlinkGene Summary
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM
Other Designations
Friedreich ataxia region gene X104 (tight junction protein ZO-2)|OTTHUMP00000021431|OTTHUMP00000063359
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Interactome
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Pathway
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