GRHPR (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human GRHPR full-length ORF ( AAH00605, 1 a.a. - 328 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.82
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GRHPR
Entrez GeneID
9380GeneBank Accession#
BC000605Protein Accession#
AAH00605Gene Name
GRHPR
Gene Alias
GLXR, GLYD, PH2
Gene Description
glyoxylate reductase/hydroxypyruvate reductase
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq
Other Designations
OTTHUMP00000046131|glycerate-2-dehydrogenase
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Interactome
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Pathway
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Disease
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Publication Reference
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Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis.
Subramanian VS, Nabokina SM, Patton JR, Marchant JS, Moradi H, Said HM.
American Journal of Physiology. Gastrointestinal and Liver Physiology 2013 Jun; 04(12):G1079.
Application：IP, PI, WB-Re, Human, HepG2 cells.
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Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis.
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