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Last updated: 2016/11/27

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ZFYVE9 rabbit monoclonal antibody

  • Catalog # : H00009372-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ZFYVE9 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ZFYVE9 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ZFYVE9 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9372
  • Gene Name:
  • ZFYVE9
  • Gene Alias:
  • MADHIP,NSP,SARA,SMADIP
  • Gene Description:
  • zinc finger, FYVE domain containing 9
  • Gene Summary:
  • This gene encodes a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. The C-terminal domain of this protein interacts with the TGFB receptor. This protein is a component of the TGFB pathway that brings the SMAD substrate to the receptor. Three alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • MAD homolog interacting protein,MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor,MADH-interacting protein,OTTHUMP00000009739,OTTHUMP00000009740,OTTHUMP00000009741,mothers against decapentaplegic homolog interact
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