ZFYVE9 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Cell lysate)
ZFYVE9 MaxPab rabbit polyclonal antibody. Western Blot analysis of ZFYVE9 expression in HeLa.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ZFYVE9 protein.
Immunogen
ZFYVE9 (NP_015562.1, 1 a.a. ~ 762 a.a) full-length human protein.
Sequence
MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESAVSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGDLMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNGKY
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (75)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ZFYVE9 MaxPab rabbit polyclonal antibody. Western Blot analysis of ZFYVE9 expression in HeLa. -
Gene Info — ZFYVE9
Entrez GeneID
9372GeneBank Accession#
NM_007323Protein Accession#
NP_015562.1Gene Name
ZFYVE9
Gene Alias
MADHIP, NSP, SARA, SMADIP
Gene Description
zinc finger, FYVE domain containing 9
Omim ID
603755Gene Ontology
HyperlinkGene Summary
This gene encodes a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SMAD proteins transmit signals from transmembrane serine/threonine kinase receptors to the nucleus. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs. The C-terminal domain of this protein interacts with the TGFB receptor. This protein is a component of the TGFB pathway that brings the SMAD substrate to the receptor. Three alternatively spliced transcripts encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
MAD homolog interacting protein|MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor|MADH-interacting protein|OTTHUMP00000009739|OTTHUMP00000009740|OTTHUMP00000009741|mothers against decapentaplegic homolog interact
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Interactome
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Pathway
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