KIF3B monoclonal antibody (M01), clone 8H4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KIF3B.
Immunogen
KIF3B (NP_004789.1, 648 a.a. ~ 747 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVDASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQSRGLVPK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KIF3B expression in transfected 293T cell line by KIF3B monoclonal antibody (M01), clone 8H4.
Lane 1: KIF3B transfected lysate (Predicted MW: 85.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KIF3B is 3 ng/ml as a capture antibody.ELISA
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Gene Info — KIF3B
Entrez GeneID
9371GeneBank Accession#
NM_004798.3Protein Accession#
NP_004789.1Gene Name
KIF3B
Gene Alias
HH0048, KIAA0359
Gene Description
kinesin family member 3B
Omim ID
603754Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq
Other Designations
OTTHUMP00000030588|kinesin-like protein KIF3B|microtubule plus end-directed kinesin motor 3B
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