SLC9A3R1 MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SLC9A3R1 protein.
Immunogen
SLC9A3R1 (NP_004243, 1 a.a. ~ 358 a.a) full-length human protein.
Sequence
MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SLC9A3R1 MaxPab polyclonal antibody. Western Blot analysis of SLC9A3R1 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of SLC9A3R1 expression in transfected 293T cell line (H00009368-T01) by SLC9A3R1 MaxPab polyclonal antibody.
Lane 1: SLC9A3R1 transfected lysate(39.38 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SLC9A3R1
Entrez GeneID
9368GeneBank Accession#
NM_004252Protein Accession#
NP_004243Gene Name
SLC9A3R1
Gene Alias
EBP50, NHERF, NHERF1, NPHLOP2
Gene Description
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Omim ID
604990Gene Ontology
HyperlinkGene Summary
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer
Other Designations
sodium/hydrogen exchanger regulatory factor 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
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Interactome
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Disease
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