LONP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-LONP1 full-length
Host
Human
Theoretical MW (kDa)
106.5
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-LONP1 antibody (H00009361-D01P) by Western Blots.
SDS-PAGE Gel
LONP1 transfected lysate.
Western Blot
Lane 1: LONP1 transfected lysate ( 106.50 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — LONP1
Entrez GeneID
9361GeneBank Accession#
NM_004793.2Protein Accession#
NP_004784.2Gene Name
LONP1
Gene Alias
LON, LONP, LonHS, MGC1498, PIM1, PRSS15, hLON
Gene Description
lon peptidase 1, mitochondrial
Omim ID
605490Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
Other Designations
LON protease|Lon protease-like protein|hLON ATP-dependent protease|mitochondrial lon peptidase 1|protease, serine, 15
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