LONP1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human LONP1 partial ORF ( NP_004784.2, 661 a.a. - 761 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
YVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLIKQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPENLQDFVGKPVFTVERMYDVTP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LONP1
Entrez GeneID
9361GeneBank Accession#
NM_004793Protein Accession#
NP_004784.2Gene Name
LONP1
Gene Alias
LON, LONP, LonHS, MGC1498, PIM1, PRSS15, hLON
Gene Description
lon peptidase 1, mitochondrial
Omim ID
605490Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
Other Designations
LON protease|Lon protease-like protein|hLON ATP-dependent protease|mitochondrial lon peptidase 1|protease, serine, 15
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