LONP1 monoclonal antibody (M01), clone 3B2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LONP1.
Immunogen
LONP1 (NP_004784.2, 661 a.a. ~ 761 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YVAQEKLAIAERYLVPQARALCGLDESKAKLSSDVLTLLIKQYCRESGVRNLQKQVEKVLRKSAYKIVSGEAESVEVTPENLQDFVGKPVFTVERMYDVTP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — LONP1
Entrez GeneID
9361GeneBank Accession#
NM_004793Protein Accession#
NP_004784.2Gene Name
LONP1
Gene Alias
LON, LONP, LonHS, MGC1498, PIM1, PRSS15, hLON
Gene Description
lon peptidase 1, mitochondrial
Omim ID
605490Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
Other Designations
LON protease|Lon protease-like protein|hLON ATP-dependent protease|mitochondrial lon peptidase 1|protease, serine, 15
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