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LONP1 rabbit monoclonal antibody

  • Catalog # : H00009361-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human LONP1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human LONP1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human LONP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 9361
  • GeneBank Accession#:
  • LONP1
  • Gene Name:
  • LONP1
  • Gene Alias:
  • Gene Description:
  • lon peptidase 1, mitochondrial
  • Gene Summary:
  • This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
  • Other Designations:
  • LON protease,Lon protease-like protein,hLON ATP-dependent protease,mitochondrial lon peptidase 1,protease, serine, 15
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