HMGN3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HMGN3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HMGN3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HMGN3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HMGN3
Entrez GeneID
9324GeneBank Accession#
HMGN3Gene Name
HMGN3
Gene Alias
DKFZp686E20226, PNAS-24, PNAS-25, TRIP7
Gene Description
high mobility group nucleosomal binding domain 3
Omim ID
604502Gene Ontology
HyperlinkGene Summary
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016772|OTTHUMP00000016773|high-mobility group protein HMGN3|thyroid hormone receptor interacting protein 7|thyroid hormone receptor interactor 7
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Interactome
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