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Last updated: 2016/12/4

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ACCN3 rabbit monoclonal antibody

  • Catalog # : H00009311-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ACCN3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ACCN3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ACCN3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9311
  • GeneBank Accession#:
  • ACCN3
  • Gene Name:
  • ACCN3
  • Gene Alias:
  • ASIC3,DRASIC,SLNAC1,TNaC1
  • Gene Description:
  • amiloride-sensitive cation channel 3
  • Gene Summary:
  • This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • amiloride-sensitive cation channel 3, testis,modulatory subunit of ASIC2a,proton-gated cation channel subunit,testis sodium channel 1
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