ITGB1BP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ITGB1BP1 full-length
Host
Human
Theoretical MW (kDa)
22.11
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ITGB1BP1 antibody (H00009270-B01) by Western Blots.
SDS-PAGE Gel
ITGB1BP1 transfected lysate.
Western Blot
Lane 1: ITGB1BP1 transfected lysate ( 22.11 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ITGB1BP1
Entrez GeneID
9270GeneBank Accession#
NM_004763Protein Accession#
NP_004754Gene Name
ITGB1BP1
Gene Alias
DKFZp686K08158, ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B
Gene Description
integrin beta 1 binding protein 1
Omim ID
607153Gene Ontology
HyperlinkGene Summary
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. [provided by RefSeq
Other Designations
OTTHUMP00000195586|bodenin|integrin cytoplasmic domain-associated protein 1|integrin cytoplasmic domain-associated protein 1-alpha|integrin cytoplasmic domain-associated protein 1-beta
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Interactome
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Disease
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