ITGB1BP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ITGB1BP1 partial ORF ( AAH12264, 101 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LPFVPPEEEFIMGVSKYGIKVSTSDQYDVLHRHALYLIIRMVCYDDGLGVGKSLLALKTTDASNEEYSLWVYQCNSLEQAQAICKVLSTAFDSVLTSEKP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ITGB1BP1
Entrez GeneID
9270GeneBank Accession#
BC012264Protein Accession#
AAH12264Gene Name
ITGB1BP1
Gene Alias
DKFZp686K08158, ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A, ICAP1B
Gene Description
integrin beta 1 binding protein 1
Omim ID
607153Gene Ontology
HyperlinkGene Summary
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. [provided by RefSeq
Other Designations
OTTHUMP00000195586|bodenin|integrin cytoplasmic domain-associated protein 1|integrin cytoplasmic domain-associated protein 1-alpha|integrin cytoplasmic domain-associated protein 1-beta
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Interactome
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Disease
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