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PSCD1 Pre-design Chimera RNAi

  • Catalog # : H00009267-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1) (PSCD1), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_017456
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9267
  • Gene Name:
  • CYTH1
  • Gene Alias:
  • B2-1,CYTOHESIN-1,D17S811E,FLJ34050,FLJ41900,PSCD1,SEC7
  • Gene Description:
  • cytohesin 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000196778,cytoadhesin 1,homolog of secretory protein SEC7,pleckstrin homology, Sec7 and coiled-coil domains 1
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