SCYE1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SCYE1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SCYE1
Entrez GeneID
9255GeneBank Accession#
NM_004757.2Protein Accession#
NP_004748.2Gene Name
SCYE1
Gene Alias
AIMP1, EMAP2, EMAPII, p43
Gene Description
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Omim ID
603605Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq
Other Designations
ARS-interacting multifunctional protein 1|OTTHUMP00000161878|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1
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Interactome
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Disease
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