SCYE1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SCYE1 full-length ORF ( AAH14051, 1 a.a. - 312 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MANNDAVLKRLEQKGAEADQIIEYLKQQVSLLKEKAILQATLREEKKLRVENAKLKKEIEELKQELIQAEIQNGVKQIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTKEQIKGGTGDEKKAKEKIEKKGEKKEKKQQSIAGSADSKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.06
Interspecies Antigen Sequence
Mouse (85); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SCYE1
Entrez GeneID
9255GeneBank Accession#
BC014051Protein Accession#
AAH14051Gene Name
SCYE1
Gene Alias
AIMP1, EMAP2, EMAPII, p43
Gene Description
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Omim ID
603605Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq
Other Designations
ARS-interacting multifunctional protein 1|OTTHUMP00000161878|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1
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Interactome
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Disease
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