SCYE1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SCYE1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SCYE1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SCYE1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SCYE1
Entrez GeneID
9255GeneBank Accession#
SCYE1Gene Name
SCYE1
Gene Alias
AIMP1, EMAP2, EMAPII, p43
Gene Description
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Omim ID
603605Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq
Other Designations
ARS-interacting multifunctional protein 1|OTTHUMP00000161878|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1
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Interactome
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Disease
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