MSC monoclonal antibody (M05), clone 4D7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MSC.
Immunogen
MSC (NP_005089.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSTGSVSDPEEMELRGLQREYPVPASKRPPLRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (86)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MSC expression in transfected 293T cell line by MSC monoclonal antibody (M05), clone 4D7.
Lane 1: MSC transfected lysate(22.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MSC is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — MSC
Entrez GeneID
9242GeneBank Accession#
NM_005098Protein Accession#
NP_005089.1Gene Name
MSC
Gene Alias
ABF-1, ABF1, MYOR, bHLHa22
Gene Description
musculin (activated B-cell factor-1)
Omim ID
603628Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq
Other Designations
activated B-cell factor 1, homolog of mouse musculin|activated B-cell factor-1|musculin
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Interactome
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Disease
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