MSC rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MSC peptide using ARM Technology.
Immunogen
A synthetic peptide of human MSC is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MSC peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MSC
Entrez GeneID
9242GeneBank Accession#
MSCGene Name
MSC
Gene Alias
ABF-1, ABF1, MYOR, bHLHa22
Gene Description
musculin (activated B-cell factor-1)
Omim ID
603628Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq
Other Designations
activated B-cell factor 1, homolog of mouse musculin|activated B-cell factor-1|musculin
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Interactome
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Disease
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