DLG5 monoclonal antibody (M01), clone 2A5
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DLG5 is 3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.96 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DLG5.
Immunogen
DLG5 (NP_004738, 1708 a.a. ~ 1809 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.96 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DLG5 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — DLG5
Entrez GeneID
9231GeneBank Accession#
NM_004747Protein Accession#
NP_004738Gene Name
DLG5
Gene Alias
KIAA0583, LP-DLG, P-DLG5, PDLG
Gene Description
discs, large homolog 5 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000060196|discs large homolog 5|discs large protein LP-DLG|large type of P-DLG|placenta and prostate DLG
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Interactome
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Disease
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