DLG5 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DLG5.
Immunogen
DLG5 (NP_004738, 1708 a.a. ~ 1809 a.a) partial recombinant protein with GST tag.
Sequence
LDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.33 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DLG5
Entrez GeneID
9231GeneBank Accession#
NM_004747Protein Accession#
NP_004738Gene Name
DLG5
Gene Alias
KIAA0583, LP-DLG, P-DLG5, PDLG
Gene Description
discs, large homolog 5 (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000060196|discs large homolog 5|discs large protein LP-DLG|large type of P-DLG|placenta and prostate DLG
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Interactome
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Disease
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