MAGI1 monoclonal antibody (M03), clone 7B4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAGI1.
Immunogen
MAGI1 (NP_004733, 761 a.a. ~ 859 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SHSTQVLPEFPPAEAQAPDQTDSSGQKKPDPFKIWAQSRSMYENRPMSPSPASGLSKGEREREINSTNFGECPIPDYQEQDIFLWRKETGFGFRILGGN
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MAGI1 monoclonal antibody (M03), clone 7B4 Western Blot analysis of MAGI1 expression in PC-12 ( Cat # L012V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAGI1 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to MAGI1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MAGI1
Entrez GeneID
9223GeneBank Accession#
NM_004742Protein Accession#
NP_004733Gene Name
MAGI1
Gene Alias
AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3
Gene Description
membrane associated guanylate kinase, WW and PDZ domain containing 1
Omim ID
602625Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
BAI1-associated protein 1|WW domain-containing protein 3|atrophin-1 interacting protein 3|membrane associated guanylate kinase inverted-1|trinucleotide repeat-containing gene 19
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Interactome
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Pathway
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Disease
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Publication Reference
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MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23.
Xu Z, Peng AW, Oshima K, Heller S.
Journal of Neuroscience 2008 Oct; 28(44):11269.
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MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23.
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