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Apoptosis
> FAIM3 monoclonal antibody (M01), clone 1E4
FAIM3 monoclonal antibody (M01), clone 1E4
Catalog # : H00009214-M01
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Specification
Gene Info
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Specification
Product Description:
Mouse monoclonal antibody raised against a partial recombinant FAIM3.
Immunogen:
FAIM3 (AAH06401, 124 a.a. ~ 223 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence:
SEYEPSWEEQPMPETPKWFHLPYLFQMPAYASSSKFVTRVTTPAQRGKVPPVHHSSPTTQITHRPRVSRASSVAGDKPRTFLPSTTASKISALEGLLKPQ
Host:
Mouse
Reactivity:
Human
Isotype:
IgG2b Kappa
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer:
In 1x PBS, pH 7.2
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
Download
Publication Reference
1.
Toso, a Functional IgM Receptor, Is Regulated by IL-2 in T and NK Cells.
Murakami Y, Narayanan S, Su S, Childs R, Krzewski K, Borrego F, Weck J, Coligan JE.J Immunol. 2012 Jun 6.
2.
Enhanced levels of both membrane-bound and soluble forms of IgM Fc receptor in patients with chronic lymphocytic leukemia.
Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H.Blood. 2011 Sep 9.
3.
SAGE analysis demonstrates increased expression of TOSO contributing to Fas mediated resistance in CLL.
Proto-Siqueira R, Panepucci RA, Careta FP, Lee A, Clear A, Morris K, Owen C, Rizzatti EG, Silva-Jr WA, Falcao RP, Zago MA, Gribben JG.Blood. 2008 Jul 15;112(2):394-7. Epub 2008 Apr 23.
Applications
Western Blot (Cell lysate)
FAIM3 monoclonal antibody (M01), clone 1E4 Western Blot analysis of FAIM3 expression in K-562 ( Cat # L009V1 ).
Protocol Download
Western Blot (Transfected lysate)
Western Blot analysis of FAIM3 expression in transfected 293T cell line by FAIM3 monoclonal antibody (M01), clone 1E4.
Lane 1: FAIM3 transfected lysate(43.1 KDa).
Lane 2: Non-transfected lysate.
Protocol Download
Western Blot (Recombinant protein)
Protocol Download
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FAIM3 is approximately 0.03ng/ml as a capture antibody.
Protocol Download
ELISA
Application Image
Western Blot (Cell lysate)
enlarge
Western Blot (Transfected lysate)
enlarge
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
enlarge
ELISA
Gene Information
Entrez GeneID:
9214
GeneBank Accession#:
BC006401
Protein Accession#:
AAH06401
Gene Name:
FAIM3
Gene Alias:
TOSO
Gene Description:
Fas apoptotic inhibitory molecule 3
Omim ID:
606015
Gene Ontology:
Hyperlink
Other Designations:
OTTHUMP00000034619,regulator of Fas-induced apoptosis
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