SLC33A1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SLC33A1 expression in transfected 293T cell line (H00009197-T01) by SLC33A1 MaxPab polyclonal antibody.
Lane 1: SLC33A1 transfected lysate(60.39 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SLC33A1 protein.
Immunogen
SLC33A1 (NP_004724.1, 1 a.a. ~ 549 a.a) full-length human protein.
Sequence
MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGSSSWKCKRNN
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SLC33A1 expression in transfected 293T cell line (H00009197-T01) by SLC33A1 MaxPab polyclonal antibody.
Lane 1: SLC33A1 transfected lysate(60.39 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SLC33A1
Entrez GeneID
9197GeneBank Accession#
NM_004733.2Protein Accession#
NP_004724.1Gene Name
SLC33A1
Gene Alias
ACATN, AT-1, AT1, SPG42
Gene Description
solute carrier family 33 (acetyl-CoA transporter), member 1
Omim ID
603690Gene Ontology
HyperlinkGene Summary
The encoded protein is required for the formation of O-acetylated (Ac) gangliosides. It is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Studies indicate that the protein is localized to the cytoplasm. [provided by RefSeq
Other Designations
acetyl-Coenzyme A transporter|acetyl-coenzyme A transporter|spastic paraplegia 42 (autosomal dominant)
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Interactome
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Pathway
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Disease
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Publication Reference
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SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway.
Pehar M, Jonas MC, Hare TM, Puglielli L.
The Journal of Biological Chemistry 2012 Aug; 287(35):29921.
Application：IEM, IF, WB, Human, H4 cells.
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AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability.
Jonas MC, Pehar M, Puglielli L.
Journal of Cell Science 2010 Oct; 123(Pt 19):3378.
Application：WB-Ce, WB-Tr, Human, Mouse, CHO, H4 cells.
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SLC33A1/AT-1 protein regulates the induction of autophagy downstream of IRE1/XBP1 pathway.
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