Rabbit monoclonal antibody raised against a human DEDD peptide using ARM Technology.
A synthetic peptide of human DEDD is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Quality Control Testing:
Antibody reactive against human DEDD peptide by ELISA and mammalian transfected lysate by Western Blot.
In 1x PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
OTTHUMP00000031821,death effector domain-containing,death effector domain-containing protein