ARHGEF2 (Human) Recombinant Protein (Q02)
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Specification
Product Description
Human ARHGEF2 partial ORF ( NP_004714, 590 a.a. - 690 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTHFQAEEDGGSGMALPTLPRGLFRSESLESPRGERLLQDAIREVEGLKDLLVGPGVELLLTPREPALPLEPDSGGNTSPGVTANGEARTFNGSIELCRAD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ARHGEF2
Entrez GeneID
9181GeneBank Accession#
NM_004723Protein Accession#
NP_004714Gene Name
ARHGEF2
Gene Alias
DKFZp547L106, DKFZp547P1516, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Gene Description
rho/rac guanine nucleotide exchange factor (GEF) 2
Omim ID
607560Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq
Other Designations
OTTHUMP00000018856|proliferating cell nucleolar antigen p40|rho/rac guanine nucleotide exchange factor 2
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Interactome
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Disease
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