ARHGEF2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ARHGEF2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ARHGEF2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ARHGEF2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ARHGEF2
Entrez GeneID
9181GeneBank Accession#
ARHGEF2Gene Name
ARHGEF2
Gene Alias
DKFZp547L106, DKFZp547P1516, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Gene Description
rho/rac guanine nucleotide exchange factor (GEF) 2
Omim ID
607560Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq
Other Designations
OTTHUMP00000018856|proliferating cell nucleolar antigen p40|rho/rac guanine nucleotide exchange factor 2
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