COX7A2L 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-COX7A2L full-length
Host
Human
Theoretical MW (kDa)
12.65
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-COX7A2L antibody (H00009167-B02) by Western Blots.
SDS-PAGE Gel
COX7A2L transfected lysate.
Western Blot
Lane 1: COX7A2L transfected lysate ( 12.65 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — COX7A2L
Entrez GeneID
9167GeneBank Accession#
NM_004718.2Protein Accession#
NP_004709.2Gene Name
COX7A2L
Gene Alias
COX7AR, COX7RP, EB1, SIG81
Gene Description
cytochrome c oxidase subunit VIIa polypeptide 2 like
Omim ID
605771Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. [provided by RefSeq
Other Designations
OTTHUMP00000158765|cytochrome c oxidase subunit VII-related protein|estrogen receptor binding CpG island
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Interactome
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Pathway
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Disease
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