COX7A2L (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human COX7A2L partial ORF ( NP_004709.2, 2 a.a. - 88 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
YYKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVYLKRGLPDQMLYR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.31
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COX7A2L
Entrez GeneID
9167GeneBank Accession#
NM_004718Protein Accession#
NP_004709.2Gene Name
COX7A2L
Gene Alias
COX7AR, COX7RP, EB1, SIG81
Gene Description
cytochrome c oxidase subunit VIIa polypeptide 2 like
Omim ID
605771Gene Ontology
HyperlinkGene Summary
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. [provided by RefSeq
Other Designations
OTTHUMP00000158765|cytochrome c oxidase subunit VII-related protein|estrogen receptor binding CpG island
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Interactome
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Pathway
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Disease
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