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PCSK7 Pre-design Chimera RNAi

  • Catalog # : H00009159-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens proprotein convertase subtilisin/kexin type 7 (PCSK7), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004716
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 9159
  • Gene Name:
  • PCSK7
  • Gene Alias:
  • LPC,PC7,PC8,SPC7
  • Gene Description:
  • proprotein convertase subtilisin/kexin type 7
  • Gene Summary:
  • The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq
  • Other Designations:
  • lymphoma proprotein convertase,prohormone convertase 8, subtilisin-like,prohormone convertase PC7,proprotein convertase PC7,proprotein convertase subtilisin/kexin type 7 precursor variant 1,subtilisin/kexin-like protease PC7
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