Immunoprecipitation of EXO1 transfected lysate using anti-EXO1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EXO1 purified MaxPab mouse polyclonal antibody (B01P) (H00009156-B01P).
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq
OTTHUMP00000037878,OTTHUMP00000037879,rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1