ATG12 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ATG12 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ATG12 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ATG12 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ATG12
Entrez GeneID
9140GeneBank Accession#
ATG12Gene Name
ATG12
Gene Alias
APG12, APG12L, FBR93, HAPG12
Gene Description
ATG12 autophagy related 12 homolog (S. cerevisiae)
Omim ID
609608Gene Ontology
HyperlinkGene Summary
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM
Other Designations
APG12 autophagy 12-like|Apg12 (autophagy, yeast) homolog
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