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ATG12 rabbit monoclonal antibody

  • Catalog # : H00009140-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human ATG12 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human ATG12 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human ATG12 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9140
  • GeneBank Accession#:
  • ATG12
  • Gene Name:
  • ATG12
  • Gene Alias:
  • APG12,APG12L,FBR93,HAPG12
  • Gene Description:
  • ATG12 autophagy related 12 homolog (S. cerevisiae)
  • Gene Summary:
  • Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM
  • Other Designations:
  • APG12 autophagy 12-like,Apg12 (autophagy, yeast) homolog
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