ARHGEF1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ARHGEF1 protein.
Immunogen
ARHGEF1 (NP_004697.2, 1 a.a. ~ 912 a.a) full-length human protein.
Sequence
MEDFARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLMALLQHVALQFEPGPLLCCLHADMLGSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQVAVGRQLEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEEKSAAVVNAIGLYMRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKGLSSILDAARWNRGEPQVPDFRHLKAEVDAEKPGATDRKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDSPDREPGADAPLELGDSSPQGPMSLESLAPPESTDEGAETESPEPGDEGEPGRSGLELEPEEPPGWRELVPPDTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFPLEELQNIFPSLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCALITETAGSLKVPAPASRPKPRPSPSSTREPLLSSSENGNGGRETSPADARTERILSDLLPFCRPGPEGQLAATALRKVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMKQLEELEEEFCRLRPLLSQLGGNSVPQPGCT
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
ARHGEF1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ARHGEF1 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of ARHGEF1 expression in transfected 293T cell line (H00009138-T01) by ARHGEF1 MaxPab polyclonal antibody.
Lane 1: ARHGEF1 transfected lysate(102.40 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ARHGEF1
Entrez GeneID
9138GeneBank Accession#
NM_004706Protein Accession#
NP_004697.2Gene Name
ARHGEF1
Gene Alias
GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5
Gene Description
Rho guanine nucleotide exchange factor (GEF) 1
Omim ID
601855Gene Ontology
HyperlinkGene Summary
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq
Other Designations
115-kD protein|Lsc homolog|Rho guanine nucleotide exchange factor 1
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Interactome
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Pathway
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Disease
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