AIFM1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PDCD8 MaxPab polyclonal antibody. Western Blot analysis of PDCD8 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of AIFM1 expression in transfected 293T cell line (H00009131-T01) by AIFM1 MaxPab polyclonal antibody.
Lane 1: PDCD8 transfected lysate(67.43 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PDCD8 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human AIFM1 protein.
Immunogen
AIFM1 (NP_004199.1, 1 a.a. ~ 613 a.a) full-length human protein.
Sequence
MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPGNLFQRWHVPLELQMTRQMASSGASGGKIDNSVLVLIVGLSTVGAGAYAYKTMKEDEKRYNERISGLGLTPEQKQKKAALSASEGEEVPQDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PDCD8 MaxPab polyclonal antibody. Western Blot analysis of PDCD8 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of AIFM1 expression in transfected 293T cell line (H00009131-T01) by AIFM1 MaxPab polyclonal antibody.
Lane 1: PDCD8 transfected lysate(67.43 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PDCD8 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — AIFM1
Entrez GeneID
9131GeneBank Accession#
NM_004208Protein Accession#
NP_004199.1Gene Name
AIFM1
Gene Alias
AIF, MGC111425, PDCD8
Gene Description
apoptosis-inducing factor, mitochondrion-associated, 1
Omim ID
300169Gene Ontology
HyperlinkGene Summary
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024007|OTTHUMP00000024008|OTTHUMP00000024009|programmed cell death 8|programmed cell death 8 (apoptosis-inducing factor)|striatal apoptosis-inducing factor
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Interactome
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Pathway
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Disease
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