CSPG6 monoclonal antibody (M02), clone 2F11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CSPG6.
Immunogen
CSPG6 (AAH47324, 711 a.a. ~ 810 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IDQLMNQMQQIETQQRKFKASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDALNDEIRQLQQE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SMC3 expression in transfected 293T cell line by CSPG6 monoclonal antibody (M02), clone 2F11.
Lane 1: SMC3 transfected lysate(141.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CSPG6 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — SMC3
Entrez GeneID
9126GeneBank Accession#
BC047324Protein Accession#
AAH47324Gene Name
SMC3
Gene Alias
BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Gene Description
structural maintenance of chromosomes 3
Gene Ontology
HyperlinkGene Summary
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq
Other Designations
OTTHUMP00000020477|bamacan proteoglycan|basement membrane-associated chondroitin proteoglycan|chondroitin sulfate proteoglycan 6 (bamacan)|chromosome-associated polypeptide
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Interactome
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Pathway
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Disease
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