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SMC3 rabbit monoclonal antibody

  • Catalog # : H00009126-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human SMC3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human SMC3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human SMC3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 9126
  • GeneBank Accession#:
  • SMC3
  • Gene Name:
  • SMC3
  • Gene Alias:
  • Gene Description:
  • structural maintenance of chromosomes 3
  • Gene Summary:
  • This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020477,bamacan proteoglycan,basement membrane-associated chondroitin proteoglycan,chondroitin sulfate proteoglycan 6 (bamacan),chromosome-associated polypeptide
  • Gene Pathway
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