Immunoprecipitation of NMI transfected lysate using anti-NMI MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with NMI purified MaxPab mouse polyclonal antibody (B01P) (H00009111-B01P).
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq
N-myc and STAT interactor,N-myc interactor,N-myc-interactor