RGN (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human RGN full-length ORF ( NP_004674.1, 1 a.a. - 299 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSIKIECVLPENCRCGESPVWEEVSNSLLFVDIPAKKVCRWDSFTKQVQRVTMDAPVSSVALRQSGGYVATIGTKFCALNWKEQSAVVLATVDNDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGALYSLFPDHHVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYSVDAFDYDLQTGQISNRRSVYKLEKEEQIPDGMCIDAEGKLWVACYNGGRVIRLDPVTGKRLQTVKLPVDKTTSCCFGGKNYSEMYVTCARDGMDPEGLLRQPEAGGIFKITGLGVKGIAPYSYAG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.7
Interspecies Antigen Sequence
Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RGN
Entrez GeneID
9104GeneBank Accession#
NM_004683.4Protein Accession#
NP_004674.1Gene Name
RGN
Gene Alias
RC, SMP30
Gene Description
regucalcin (senescence marker protein-30)
Omim ID
300212Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein. [provided by RefSeq
Other Designations
OTTHUMP00000023195|OTTHUMP00000023196|regucalcin|senescence marker protein-30
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