Immunoprecipitation of UNC119 transfected lysate using anti-UNC119 MaxPab mouse polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with UNC119 monoclonal antibody (M01), clone 2F9-2A9 (H00009094-M01).
This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
retinal protein 4,unc119 (C.elegans) homolog,unc119 homolog