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SART1 (Human) Recombinant Protein (Q01)

  • Catalog # : H00009092-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human SART1 partial ORF ( NP_005137.1, 701 a.a. - 800 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 36.74
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00009092-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 9092
  • Gene Name:
  • SART1
  • Gene Alias:
  • Ara1,HOMS1,MGC2038,SART1259,SNRNP110,Snu66
  • Gene Description:
  • squamous cell carcinoma antigen recognized by T cells
  • Gene Summary:
  • This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq
  • Other Designations:
  • IgE autoantigen,SART1(259) protein,SART1(800) protein,U4/U6.U5 tri-snRNP-associated 110 kDa protein,small nuclear ribonucleoprotein 110kDa (U4/U6.U5),squamous cell carcinoma antigen recognised by T cells,squamous cell carcinoma antigen recognized by T cel
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