PKMYT1 (Human) Recombinant Protein (Q01)

Catalog # H00009088-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

  • Specification

    Product Description

    Human PKMYT1 partial ORF ( NP_004194.3, 400 a.a. - 499 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    PASWLQPLGPPATPPGSPPCSLLLDSSLSSNWDDDSLGPSLSPEAVLARTVGSTSTPRSRCTPRDALDLSDINSEPPRGSFPSFEPRNLLSLFEDTLDPT

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.74

    Interspecies Antigen Sequence

    Mouse (89); Rat (89)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — PKMYT1

    Entrez GeneID

    9088

    GeneBank Accession#

    NM_004203

    Protein Accession#

    NP_004194.3

    Gene Name

    PKMYT1

    Gene Alias

    DKFZp547K1610, FLJ20093, MYT1

    Gene Description

    protein kinase, membrane associated tyrosine/threonine 1

    Omim ID

    602474

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

    Other Designations

    membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase|protein kinase Myt1

  • Interactome
  • Pathway
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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