DIRAS3 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DIRAS3.
Immunogen
DIRAS3 (NP_004666, 130 a.a. ~ 229 a.a) partial recombinant protein with GST tag.
Sequence
FYELICKIKGNNLHKFPIVLVGNKSDDTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCIIM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DIRAS3
Entrez GeneID
9077GeneBank Accession#
NM_004675Protein Accession#
NP_004666Gene Name
DIRAS3
Gene Alias
ARHI, NOEY2
Gene Description
DIRAS family, GTP-binding RAS-like 3
Omim ID
605193Gene Ontology
HyperlinkGene Summary
This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. It is a maternally imprinted gene and its expression is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq
Other Designations
OTTHUMP00000011138|ras homolog gene family, member I
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Interactome
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Disease
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Publication Reference
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Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice.
Li J, Ramani K, Sun Z, Zee C, Grant EG, Yang H, Xia M, Oh P, Ko K, Mato JM, Lu SC.
The American Journal of Pathology 2010 May; 176(5):2456.
Application:WB-Tr, Human, Huh-7 cells.
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Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice.
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